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Giostar Mexico
Giostar Mexico

Research

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More than 100 scientific publications where our Director and laboratory team have played an essential role.

Giostar Mexico stands at the forefront of regenerative medicine through continuous research, innovation, and global collaboration. Our scientific foundation ensures that every treatment protocol is backed by rigorous evidence, ethical standards, and decades of pioneering work in cellular biology.

  • Evidence-based protocols developed and refined by global experts in regenerative science
  • Cutting-edge research and development driving advancements in cellular and molecular health
  • Bridging clinical practice with scientific innovation to deliver safe and effective treatments
  • Pioneering discoveries in stem cell and cellular regeneration led by Dr. Anand Srivastava and his international research team
  • Commitment to transparency and ethics in every stage of research and application

Scientific Publications & Research Articles

Explore a selection of published studies and research contributions from Giostar’s global team. Each publication reflects our ongoing commitment to advancing regenerative medicine through evidence-based science, innovation, and ethical research practices.

Great Wealth Is Health
Over the years, the pharmaceutical market and the medical equipment have evolved thanks to the dedication and commitment of several experts, organizations and businesses in medical research.
The contemporary population meanwhile continues to seek for safe, reliable, comfortable and better quality of care.
Social funds and governmental bodies enjoy the elevation of life expectancy of their population but continue to spend more money.
Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study.
Seetharaman R, Mahmood A, Kshatriya P, Patel D, Srivastava A. Case Reports in Dermatological Medicine May 2019
Article ID 8309103
https://doi.org/ 10.1155/ 2019/ 8309103.
Diabetes: stem cells offering healthy promises
Saraswat A, Srivastava A. J Stem Cell Res Ther 2018 May,
4(3):46-47.
DOI: 10.15406/jsrt.2018.04.00113.
Role of cell based approaches in cancer immunotherapy
Mahmood A, Srivastava A, Srivastava S, Pandya H, Neel Khokhani, Divyang Patel, Rangnath Mishra. J Stem Cell Res Ther. May 2017
2(5): 00077
DOI: 10.15406/jsrt.2017.02.00077.
Inflammatory Bowel Diseases: Current Therapeutic Approaches and Potential of using Stem Cells
Mishra T, Sarswat A, Mishra K, Srivastava AS. J Stem Cell Res Ther. 2017 Feb
2(2): 00057
DOI:10.15406/jsrt.2017.02.00057
Cardiovascular diseases: Recent developments in regenerative medicine.
Mahmood, A., Pandya, H., Rajasekar,S., Patel, D., Srivastava A.. Journal of Stem Cell Research & Therapeutics. 2017, July
3(2):00095.
DOI: 10.15406/jsrt.2017.03.00095
Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice
Sharma V, Nayak J, DeRossi C, Charbono A, Ichikawa M, Ng BG, Grajales-Esquivel E, Srivastava A, Wang L, He P, Scott DA, Russell J, Contreras E, Guess CM, Krajewski S, Del Rio-Tsonis K, Freeze HH. FASEB J. 2014 Apr
28(4):1854-69
DOI: 10.1096/fj.13-245514
Basal expression of pluripotency-associated genes can contribute to stemness property and differentiation potential
Dadheech N, Srivastava A, Belani M, Gupta S, Pal R, Bhonde RR, Srivastava AS, Gupta S. Stem Cells Dev. 2013 Jun 15
22(12):1802-17
DOI:10.1089/scd.2012.0261
Therapeutic potential of mesenchymal stem cells in regenerative medicine.
Patel DM, Shah J, Srivastava AS., Stem Cells Int. 2013 Feb
496218
DOI: 10.1155 / 2013 / 496218
Claudins and cancer: Fall of the soldiers entrusted to protect the gate and keep the barrier intact.
Singh AB, Dhawan P. Semin Cell Dev Biol. 2015 May 27
pii: S1084-9521(15)00098-1
doi: 10.1016/j.semcdb.2015.05.001
Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis
Bhat AA, Pope JL, Smith JJ, Ahmad R, Chen X, Washington MK, Beauchamp RD, Singh AB, Dhawan P. Oncogene. 2014 Dec 15.
doi: 10.1038/onc.2014.385
Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis.
Pope JL, Ahmad R, Bhat AA, Washington MK, Singh AB, Dhawan P. Mol Cancer. 2014 Jul 6
13:167
doi: 10.1186/1476-4598-13-167
Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis
Ahmad R, Chaturvedi R, Olivares-Villagómez D, Habib T, Asim M, Shivesh P, Polk DB, Wilson KT, Washington MK, Van Kaer L, Dhawan P, Singh AB. Mucosal Immunol. 2014 Nov
7(6):1340-53
doi: 10.1038/mi.2014.21
Epub 2014 Mar 26
Embryonic Stem Cells in Medicinal Chemistry and Drug Development
Srivastava AS. Curr Top Med Chem
2011 Mar 30
Cancer Stem Cells and Colorectal Cancer: An Overview
Dhawan P, Ahmad R, Srivastava AS, Singh AB. Curr Top Med Chem
2011 Mar 30.
Artificial Hematopoietic Stem Cell Niche: Bioscaffolds to Microfluidics to Mathematical Simulations
Didwania M, Didwania A, Mehta G, Basak GW, Yasukawa S, Takayama S, de Necochea-Campion R, Srivastava A, Carrier E. Curr Top Med Chem
2011 Mar 30
Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells
Mandal S, Lindgren AG, Srivastava AS, Clark AT, Banerjee U. Stem Cells. 2011 Mar
29(3):486-95
Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.
Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC. Bioinformatics
30:2393-8 (2014).
ER2 activation results in β-catenin-dependent changes in pulmonary epithelial permeability.
inigan JH, Vasu VT, Thaikoottathil JV, Mishra R, Shatat MA, Mason RJ, Kern JA Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15
308(2):L199-207
doi: 10.1152/ajplung.00237.2014
Epub 2014 Oct 17
Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling
Pope JL, Bhat AA, Sharma A, Ahmad R, Krishnan M, Washington MK, Beauchamp RD, Singh AB, Dhawan P. Gut. 2014 Apr
63(4):622-34
doi: 10.1136/gutjnl-2012-304241
Epub 2013 Jun 13
Role of resveratrol-induced CD11b+ Gr-1+ myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3+ T cells and amelioration of chronic colitis in IL-10-/- mice
Singh, U.P., Narendra P. Singh, Balwan Singh, Lorne J. Hofseth, Robert L Price, Mitzi Nagarkatti, and Prakash S. Nagarkatti. (2011)
(Accepted in Brain, Behavior and Immunity)
Activation of Aryl Hydrocarbon Receptor Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 genes and Amelioration of Experimental Colitis
Singh, U.P.*, Narendra P. Singh*, Balwan Singh, Robert L Price, Mitzi Nagarkatti,and Prakash S. Nagarkatti. (2011)
(Accepted in PLoS ONE)
Resveratrol (trans-3, 5, 4′- trihydroxystilbene) induces SIRT1 and down-regulates NF-kB activation toabrogate DSS-induced colitis
Singh, U.P., Narendra P. Singh, Balwan Singh, Lorne J. Hofseth, Robert L Price,Mitzi Nagarkatti, and Prakash S. Nagarkatti (2010) J. Pharmacology & Exp. Therapeutics
332(3): 829-839
Resveratrolsuppresses colitis and colon cancer associated with colitis
Xiangli Cui, Yu Jin, Anne B. Hofseth, Alexander Chumanevich, Mitzi Nagarkatti,Prakash S. Nagarkatti, Udai P. Singh, and Lorne J. Hofseth (2010) Cancer-Prevention Research
3(4): 549-559
Stem cells as potential therapeutic targets for Inflammatory Bowel Disease
Singh, U.P., Narendra P. Singh, Balwan Singh, Mishra Manoj, Mitzi Nagarkatti, Prakash S. Nagarkatti and Singh SR (2010) Frontiers in Biosciences S
(2): 993-1008
Taming the beast within: resveratrol suppresses colitis and prevents colon cancer
Lorne J. Hofseth, Singh, U.P., Narendra P. Singh, Mitzi Nagarkatti, and Prakash S. Nagarkatti (2010) Aging
2(4): 183-184
Systemic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate
Yu Jin, Xiangli Cui, Udai P. Singh, Brook Harmon, Philip Cavicchia, Anne B. Hofseth, Venkata Kotakadi, Brandy Stroud, Alexander A. Chumanevich,James R. Hebert, Thomas G. Hurley, and Lorne J. Hofseth (2010) Molecular Nutrition and Food Research
(54): 1-9
Autologous hematopoietic stem cell transplantation as an intensive consolidation therapy for adult patients in remission from acute myelogenous leukemia
Jung AS, Holman PR, Castro JE, Carrier EK, Bashey A, Lane TA, Nelson CL, Pu M, Messer K, Corringham SM, Ball ED. Biol Blood Marrow Transplant. 2009 Oct
15(10):1306-13
Epub 2009 Aug 3
Human embryonic stem cells hemangioblast express HLA-antigens
Basak GW, Yasukawa S, Alfaro A, Halligan S, Srivastava AS, Min WP, Minev B, Carrier E. J Transl Med. 2009 Apr 22
7:27
Multiple myeloma bone marrow niche
Basak GW, Srivastava AS, Malhotra R, Carrier E. Curr Pharm Biotechnol. 2009 Apr
10(3):345-6
CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation
Bashey A, Medina B, Corringham S, Pasek M, Carrier E, Vrooman L, Lowy I, Solomon SR, Morris LE, Holland HK, Mason JR, Alyea EP, Soiffer RJ, Ball ED. Blood. 2009 Feb 12
113(7):1581-8
Epub 2008 Oct 30
Endothelin-1 (1-31): from chymase-dependent synthesis to cardiovascular pathologies.
D’Orlans-Juste P, Houde M, Rae GA, Bkaily G, Carrier E, Simard E. Vascul Pharmacol. 2008 Aug-Sep;
49(2-3):51-62
Epub 2008 Jul 12. Review
CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis
Singh U.P., Singh, R., Singh, S., Karls R.K., Quinn F.D., Taub, D.D., and J.W. Lillard, Jr. (2008) BMC Immunol
9(1): 25
CCL5 regulation of mucosal chlamydial immunity and infection
Singh U.P.*, Sakthivel, S.K.*, Singh, S., Taub, D.D., Igietseme, J.U., and J.W. Lillard, Jr. (2008) BMC Microbiol. 8:136.
8:136
CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis
Singh U.P., Singh, R., Singh, S., Karls R.K., Quinn F.D., Taub, D.D., and J.W. Lillard, Jr. (2008) BMC Immunol
9(1): 25
Chronic colitis and CXCL10-producing mucosal T helper, NK and NKT cells in IL10-/- mice can be abrogated by CXCL10 blockade
Singh U.P., Singh, S., Singh, R., Cong, Y., Taub, D.D. and J.W. Lillard, Jr. (2008) Journal of Interferon and Cytokine Research
28(1): 31-43.
Changes in serum leptin, insulin, androstenedione, and luteinizing hormone during ovarian cycle in the bat, Taphozous longimanus
Singh U.P., A. Krishna, and Kunwar P. Bhatnagar (2008) Acta Biologica Hungarica Indicate equal contribution
59(1): 1-16.* Indicate equal contribution
Prospects of embryonic stem cells in treatment of hematopoietic disorders
Srivastava AS, Malhotra R, Esmaeli-Azad B, Lane T, Carrier E. Curr Pharm Biotechnol. 2007 Oct
8(5):305-17
Peripheral blood progenitor cell mobilization with intermediate-dose cyclophosphamide, sequential granulocyte-macrophage-colony-stimulating factor and granulocyte-colony-stimulating factor, and scheduled commencement of leukapheresis in 225 patients undergoing autologous transplantation
Bashey A, Donohue M, Liu L, Medina B, Corringham S, Ihasz A, Carrier E, Castro JE, Holman PR, Xu R, Law P, Ball ED, Lane TA. Transfusion. 2007 Nov
47(11):2153-60
Ovarian recovery after stem cell transplantation
Liu J, Malhotra R, Voltarelli J, Stracieri AB, Oliveira L, Simoes BP, Ball ED, Carrier E. Bone Marrow Transplant. 2008 Feb
41(3):275-8
Epub 2007 Oct 22
Embryonic stem cells ameliorate piroxicam-induced colitis in IL10-/- KO mice
Srivastava AS, Feng Z, Mishra R, Malhotra R, Kim HS, Carrier E. Biochem Biophys Res Commun. 2007 Oct 5
361(4):953-9
Epub 2007 Aug 1
Thrombopoietin enhances generation of CD34+ cells from human embryonic stem cells
Srivastava AS, Nedelcu E, Esmaeli-Azad B, Mishra R, Carrier E. Stem Cells. 2007 Jun
25(6):1456-61
Epub 2007 Mar 22
CXCR3 Axis: Role in Inflammatory Bowel Disease and its Therapeutic Implication
Singh U.P., Singh S, Chandrasekar Venkataraman and James W. Lillard, Jr. (2007) Endocrine, Metabolic & Immune Disorder: Drug Target
7(2): 111- 123
Influence of Mycobacterium avium paratuberculosis on colitis development and specifics immune responses during disease
Singh U.P., Singh S, Singh R, Frederick D. Quinn, Morris E. Potter & James W. Lillard, Jr. (2007) Infection and Immunity
75 (8): 3722-3278
Dexamethasone facilitates erythropoiesis in murine embryonic stem cells differentiating into hematopoietic cells in vitro
Srivastava AS, Kaushal S, Mishra R, Lane TA, Carrier E. Biochem Biophys Res Commun. 2006 Jul 28
346(2):508-16
Epub 2006 Jun 2
Transplanted embryonic stem cells successfully survive, proliferate, and migrate to damaged regions of the mouse brain
Srivastava AS, Shenouda S, Mishra R, Carrier E. Stem Cells. 2006 Jul
24(7):1689-94
Epub 2006 Mar 30
Non-anthracycline based remission induction therapy for newly diagnosed patients with acute myeloid leukemia aged 60 or older
Bashey A, Liu L, Ihasz A, Medina B, Corringham S, Keese K, Carrier E, Castro JE, Holman P, Lane TA, Hassidim K, Ball ED. Leuk Res. 2006 Apr
30(4):503-6
Epub 2005 Nov 21
Improving the efficiency of PBPC collection by pre-apheresis peripheral blood and mid-apheresis product measurements of CD34 cells
Lane TA, Bashey A, Carrier E, Holman P, Castro J, Mullen M, Ward DM, Ada O, Ball ED. Cytotherapy. 2004
6(4):318-27
In utero DNA immunisation. Immunity over tolerance in fetal life
Rizzi M, Gerloni M, Srivastava AS, Wheeler MC, Schuler K, Carrier E, Zanetti M. Vaccine. 2005 Jul 21
23(33):4273-82
Hematopoietic stem cell transplantation for multiple sclerosis
Burt RK, Cohen B, Rose J, Petersen F, Oyama Y, Stefoski D, Katsamakis G, Carrier E, Kozak T, Muraro PA, Martin R, Hintzen R, Slavin S, Karussis D, Haggiag S, Voltarelli JC, Ellison GW, Jovanovic B, Popat U, McGuirk J, Statkute L, Verda L, Haas J, Arnold R. Arch Neurol. 2005 Jun
62(6):860-4
In utero gene therapy: prospect and future
Chauhan DP, Srivastava AS, Moustafa ME, Shenouda S, Carrier E. Curr Pharm Des. 2004
10(29):3663-72. Review
Chimerism and tolerance post-in utero transplantation with embryonic stem cells
Moustafa ME, Srivastava AS, Nedelcu E, Donahue J, Gueorguieva I, Shenouda SS, Minev B, Carrier E. Transplantation. 2004 Nov 15
78(9):1274-82
T-cell depletion improves outcome after autologous stem cell transplant in patients with systemic lupus erythematosus (SLE)
Kamrava MR, Anderson EM, Kalunian K, Bashey A, Holman P, Medina B, Ball ED, Carrier E. Bone Marrow Transplant. 2005 Jan;35(2):205-6. No abstract available. Erratum in: Bone Marrow Transplant. 2005 Feb
35(3):321
A regulatory role of Wnt signaling pathway in the hematopoietic differentiation of murine embryonic stem cells
Feng Z, Srivastava AS, Mishra R, Carrier E. Biochem Biophys Res Commun. 2004 Nov 26
324(4):1333-9
In utero detection of T7 phage after systemic administration to pregnant mice
Srivastava AS, Chauhan DP, Carrier E. Biotechniques. 2004 Jul
37(1):81-3
High-dose CEB vs BEAM with autologous stem cell transplant in lymphoma
Wang EH, Chen YA, Corringham S, Bashey A, Holman P, Ball ED, Carrier E. Bone Marrow Transplant. 2004 Oct
34(7):581-7
Induction of apoptosis in human lung cancer cells by curcumin
Radhakrishna Pillai G, Srivastava AS, Hassanein TI, Chauhan DP, Carrier E. Cancer Lett. 2004 May 28
208(2):163-70
Purification and properties of cytosolic alanine aminotransferase from the liver of two freshwater fish, Clarias batrachus and Labeo rohita
Srivastava AS, Oohara I, Suzuki T, Shenouda S, Singh SN, Chauhan DP, Carrier E. Comp Biochem Physiol B Biochem Mol Biol. 2004 Feb
137(2):197-207
Immunological factors that affect the in vivo fate of T7 phage in the mouse
Srivastava AS, Kaido T, Carrier E. J Virol Methods. 2004 Jan
115(1):99-104
FLAG chemotherapy followed by allogeneic stem cell transplant using nonmyeloablative conditioning induces regression of myelofibrosis with myeloid metaplasia
Tanner ML, Hoh CK, Bashey A, Holman P, Sun C, Broome HE, Lane T, Ball ED, Carrier E. Bone Marrow Transplant. 2003 Sep
32(6):581-5
Development of a phase III trial of hematopoietic stem cell transplantation for systemic lupus erythematosus
Burt RK, Marmont A, Arnold R, Heipe F, Firestein GS, Carrier E, Hahn B, Barr W, Oyama Y, Snowden J, Kalunian K, Traynor A. Bone Marrow Transplant. 2003 Aug
32 Suppl 1:S49-51
Tolerance and immunity following in utero transplantation of allogeneic fetal liver cells: the cytokine shift
Sefrioui H, Donahue J, Gilpin EA, Srivastava AS, Carrier E. Cell Transplant. 2003
12(1):75-82