Stem Cell Therapy for Autism

 

Table of Contents Stem Cell Treatment for Autism Autism Facts Stem Cell Therapy for Autism Cost Stem Cell Therapy Financing Autism Treatment in Mexico Stem Cell Therapy for Autism Research References

Stem Cell Treatment for Autism

With stem cell therapy for autism, the application of mesenchymal stem cells can improve the overall regulation of the immune system and the neural connectivity in the brain. Our milestone is to help children with autism in improving their day to day verbal communication, and social skills also proved to reduce hyperactivity and repetitive behaviors, and boost the immune system.

ASD patients show a decreased number of Purkinje cells in the cerebellum**. These changes could reflect defective cortical organization in ASDs development. In addition, autism is associated with dysregulation in the maturation and plasticity of dendritic spine morphology.*** 

Restoring injured brain functioning could be achieved by stem-cell-based cell replacement.**** Indeed, transplanted MSCs are able to promote synaptic plasticity and functional recovery and rescue cerebellar Purkinje cells.****** Challenging newest study from Deng et al. suggests that granulocyte colony-stimulating factor (G-CSF) is able to mobilize MSCs into peripheral blood. These mobilized MSCs are incorporated and integrate into damaged brain in craniocerebral injured mice, ameliorating the effect of trauma.*******

It is noteworthy that MSC ability to migrate to the sites of injury and participate in the repair process is a key issue in tissue repair.******** Also by this way, MSC therapy could restore the altered brain organization seen in autistic subjects.

• At least two key-action mechanisms of stem cells could be useful for ASD therapy: paracrine effect (the secretome tool: cytokines, chemokines, and growth factors released by stem cells and responsible of repair/restoration of injured tissues) and immunomodulatory properties. Source 
• ASDs show immune system abnormalities and strong proinflammatory cytokine production. Source.
• ASD subjects show an imbalance in innate and adaptive immunity, as CD3+, CD4+, and CD8+ T cells, as well as natural killer (NK) cells, are altered. Source.
• The immune modulatory capacity of stem cells could restore these ASD–immune alterations. Stem cells are able to strongly inhibit CD8+ and CD4+ T lymphocytes and NK cell overactivation and proliferation by inhibiting proinflammatory tumor necrosis factor alpha and interferon gamma molecules and increasing anti-inflammatory IL-10 levels. Source.

What to look forward to

The experiences of Giostar Mexico patients have shown that stem cell therapy can help to improve cognitive function and reduce behavioral symptoms in patients with autism. The therapy works by differentiating stem cells into neurons, which can help to regenerate damaged brain tissue and improve brain function.

Patients who received stem cell therapy reported a significant improvement in their symptoms, including improved cognitive function, improved social interaction, and reduced repetitive behaviors. The therapy has the potential to improve the quality of life of patients with autism and reduce the need for medication. While more research is needed, these results provide hope for those suffering from autism.

How much does stem cell therapy cost?

The cost of Stem Cell Therapy needs to be determined by our expert medical team, as prices depend on the specific condition and personalized medical recommendations. Our dedicated team of medical professionals carefully evaluates each patient's unique health situation to recommend the most effective therapy. Stem Cell Therapy includes the following:

• Laboratory protocol by Dr. Anand (activation of the stem cells to direct them towards the affected tissue or organ)
• 1 - 3 stem cell vials (35 - 105 million stem cells)
• 1 - 10 billion exosomes (volume depends on the doctor's personal evaluation of each patient)
• Oxygen Therapy
• Body preparation
• Medical Consultation
• Dietitian Follow-up post-therapy
• Transportation hotel-clinic in local shuttle
• Lodging (available in our Clinic in Algodones) at Hotel Hacienda or Hotel Cielito Lindo
• Preferential prices for future reinforcements/applications

 

 

Giostar's Approach to Stem Cell Therapy

Being part of the last three decades of innovative discoveries in the research-based area of regenerative medicine, Stem Cell Therapy promotes the reduction and stoppage of degenerative diseases or conditions, such as ALS, physical injuries and aging, bolstering the regeneration of damaged tissues, bodily processes and overall well-being.

Giostar Mexico specializes in medical tourism, receiving patients from all over the world. With the acquired understanding based on scientific research, we are able to provide personalized protocols to each patient. Through specialized allogenic mesenchymal adult stem cells, our regenerative therapy concentrates stem cells in the targeted area, organ or immune system, helping the body stop the progression of a disease or condition and begin regeneration. 

Stem cell therapy in Mexico

• Is stem cell therapy safe and legal in Mexico?

An important question our patients ask before coming to our clinics is: Is stem cell therapy safe? We also understand that, perhaps, the real question is: 

• Is stem cell therapy legal in Mexico? Yes and of course! 

In Giostar Mexico, we ask for each applicant to submit a health history form, from which our medical directors personally evaluate the viability of each applicant. This means that stem cell therapy may not be for everyone. 

Stem cell therapy is thoroughly regulated by the Mexican FDA equivalent: COFEPRIS. Due to advanced legislation, Mexico enjoys sufficient regulatory framework to offer applications otherwise unavailable in countries such as the US or Canada, for example, local direct applications (hands for arthritis, shoulder pain, knee pain), lumbar and cervical applications, all of which have proven better results for patients, than just receiving stem cell therapy intravenously.

Why Choose GIOSTAR Mexico?

GIOSTAR Mexico stands out for its commitment to personalized therapy for various diseases. Recognizing that each patient is unique, we develop tailored protocols to cater to individual differences influenced by genetics and other factors.

To further facilitate access to stem cell therapy, we are pleased to announce our partnership with United Credit, offering eligible US citizens up to $25,000.00 USD in credit for treatment costs. Stem cell therapy, a cornerstone of regenerative medicine, aims to slow down or halt deterioration and even regenerate damaged tissues and organs. By completing our health history form, patients enable our medical staff to determine therapy suitability and craft personalized treatment plans to address specific health conditions.

Stem Cell Therapy for Autism Research References

* Dario Siniscalco, Anna Sapone, Alessandra Cirillo, Catia Giordano, Sabatino Maione, Nicola Antonucci, "Autism Spectrum Disorders: Is Mesenchymal Stem Cell Personalized Therapy the Future?", BioMed Research International, vol. 2012, Article ID 480289, 6 pages, 2012. https://doi.org/10.1155/2012/480289

** M. L. Bauman and T. L. Kemper, “Neuroanatomic observations of the brain in autism: a review and future directions,” International Journal of Developmental Neuroscience, vol. 23, no. 2-3, pp. 183–187, 2005.

*** D. A. Fortin, T. Srivastava, and T. R. Soderling, “Structural modulation of dendritic spines during synaptic plasticity,” Neuroscientist. In press.

**** A. T. Sørensen, N. Rogelius, C. Lundberg, and M. Kokaia, “Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons,” Experimental Neurology, vol. 229, no. 2, pp. 274–281, 2011.

******R. C. Rodrigues Hell, M. M. Silva Costa, A. M. Goes, and A. L. Oliveira, “Local injection of BDNF producing mesenchymal stem cells increases neuronal survival and synaptic stability following ventral root avulsion,” Neurobiology of Disease, vol. 33, no. 2, pp. 290–300, 2009.  

******* J. Deng, Z. M. Zou, T. L. Zhou et al., “Bone marrow mesenchymal stem cells can be mobilized into peripheral blood by G-CSF in vivo and integrate into traumatically injured cerebral tissue,” Neurological Sciences, vol. 32, no. 4, pp. 641–651, 2011.

******** L. Li and J. Jiang, “Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction mechanisms,” Frontier Medical, vol. 5, pp. 33–39, 2011.